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pentobarbital will decrease the extent or effect of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Effect of coadministering a robust CYP3A4 inducer with fedratinib hasn't been researched.pentobarbital will reduce the extent or impact of tadalafil by affecting hepatic/intestinal enzyme CYP

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